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Explore overview, symptoms, causes, treatment, diagnosis, prevention, and FAQ articles for this condition.
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Symptoms of Systemic sclerosis
The symptoms of systemic sclerosis arise from three linked biological processes: abnormal activation of the immune system, damage to small blood vessels, and excessive deposition of collagen and other connective tissue proteins in the skin and internal organs. The most recognizable…
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Causes of Systemic sclerosis
What causes systemic sclerosis? The condition arises from a combination of immune system dysfunction, blood vessel injury, and abnormal activation of fibroblasts that produce excess connective tissue. In other words, systemic sclerosis develops when the body’s normal mechanisms for immune defense,…
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FAQ about Systemic sclerosis
This FAQ article explains the most common questions people ask about systemic sclerosis, also called scleroderma. It covers what the condition is, why it happens, how it is diagnosed, what treatment can do, and what to expect over time. The focus…
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What is Systemic sclerosis
Systemic sclerosis is a chronic autoimmune connective tissue disorder in which the immune system, blood vessels, and fibrous tissues become abnormally interrelated. The central biological features are immune activation , damage to small blood vessels , and excess collagen deposition that…
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Diagnosis of Systemic sclerosis
Systemic sclerosis is diagnosed by combining clinical observation with targeted tests that assess immune activity, blood vessel changes, skin involvement, and internal organ function. It is a connective tissue disease in which the immune system, blood vessels, and fibroblasts interact abnormally,…
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Treatment for Systemic sclerosis
Treatment of systemic sclerosis uses a combination of immunosuppressive drugs, vasodilator therapies, fibrosis-directed strategies, organ-specific interventions, and long-term monitoring. These treatments do not cure the disease, but they are designed to influence the biological processes that drive it: immune activation, vascular…
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Prevention of Systemic sclerosis
Systemic sclerosis, also called scleroderma, is an autoimmune disease in which the immune system becomes dysregulated, blood vessels are damaged, and excess collagen is deposited in the skin and internal organs. Because the condition develops through a combination of immune, vascular,…