vascular skin disorder
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Explore overview, symptoms, causes, treatment, diagnosis, prevention, and FAQ articles for this condition.
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What is Necrobiosis lipoidica
Necrobiosis lipoidica is a chronic inflammatory skin disorder that primarily affects the dermis , the deeper structural layer of the skin, and often the small blood vessels that run through it. It is characterized by a combination of degeneration of collagen…
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Symptoms of Necrobiosis lipoidica
Necrobiosis lipoidica is a chronic inflammatory skin condition whose symptoms usually begin as small, slowly enlarging patches on the lower legs, most often on the shins. The typical symptoms include yellow-brown or reddish plaques, a shiny and thinned surface, visible blood…
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Causes of Necrobiosis lipoidica
What causes Necrobiosis lipoidica? The condition is thought to arise from a combination of abnormal blood vessel function, immune-mediated inflammation, and changes in connective tissue metabolism, with diabetes being the strongest associated disease. In other words, Necrobiosis lipoidica does not result…
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Treatment for Necrobiosis lipoidica
What treatments are used for Necrobiosis lipoidica? Management usually combines topical or intralesional anti-inflammatory medications, measures to protect the skin, treatment of associated metabolic disease such as diabetes when present, and in selected cases procedures such as phototherapy, systemic immunomodulatory drugs,…
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Diagnosis of Necrobiosis lipoidica
Necrobiosis lipoidica is usually identified through a combination of clinical examination and, when needed, tissue analysis. It is a chronic inflammatory skin disorder in which degeneration of collagen in the dermis is accompanied by granulomatous inflammation and changes in the small…
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Prevention of Necrobiosis lipoidica
Necrobiosis lipoidica is a chronic inflammatory skin condition that most often affects the shins and is strongly associated with diabetes, although it can also occur without diabetes. The disorder is not usually considered fully preventable in the strict sense, because its…
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FAQ about Necrobiosis lipoidica
Necrobiosis lipoidica is an uncommon inflammatory skin condition that most often affects the lower legs, especially the shins. It can be confusing because it may look like a rash, a scar, or another type of chronic ulcer, and it often develops…